fogyasztás Orvos megsért overall mutation load and p53 mutations visszatartása Újdonság Különféle
TP53 mutational landscape of metastatic head and neck cancer reveals patterns of mutation selection - eBioMedicine
Low-burden TP53 mutations in CLL: clinical impact and clonal evolution within the context of different treatment options - ScienceDirect
Homogenous TP53mut-associated tumor biology across mutation and cancer types revealed by transcriptome analysis | Cell Death Discovery
IJMS | Free Full-Text | Do Mutations Turn p53 into an Oncogene?
Analysis of P53 mutations and their expression in 56 colorectal cancer cell lines | PNAS
Mutant p53 Gain of Function in Two Mouse Models of Li-Fraumeni Syndrome: Cell
Probability Distributions of p53 Mutations and Their Corresponding Shannon Entropies in Different Cancer Cell Types | SpringerLink
A TP53-Associated Immune Prognostic Signature for the Prediction of Overall Survival and Therapeutic Responses in Muscle-Invasive Bladder Cancer - Frontiers
Targeting Cavity-Creating p53 Cancer Mutations with Small-Molecule Stabilizers: the Y220X Paradigm | ACS Chemical Biology
Mutations of the p53 Gene as a Prognostic Factor in Aggressive B-Cell Lymphoma | NEJM
TP53 exon-6 truncating mutations produce separation of function isoforms with pro-tumorigenic functions | eLife
Prognostic value of TP53 mutation location in breast cancer | CMAR
Mutational processes shape the landscape of TP53 mutations in human cancer | Nature Genetics
High prevalence of TP53 loss and whole-genome doubling in early-onset colorectal cancer | Experimental & Molecular Medicine
TP53 mutational landscape of metastatic head and neck cancer reveals patterns of mutation selection - eBioMedicine
Frontiers | Promising New Tools for Targeting p53 Mutant Cancers: Humoral and Cell-Based Immunotherapies
Germline TP53 mutations undergo copy number gain years prior to tumor diagnosis | Nature Communications
p53 Is the Most Frequently Mutated Gene in Cancer, but Can We Target It?
Survival of patients with p53 mutations in the DNA-binding motifs... | Download Scientific Diagram
Gain of function in somatic TP53 mutations is associated with immune‐rich breast tumors and changes in tumor‐associated macrophages - Behring - 2019 - Molecular Genetics & Genomic Medicine - Wiley Online Library
p53 Is the Most Frequently Mutated Gene in Cancer, but Can We Target It?
Omics analyses of a somatic Trp53R245W/+ breast cancer model identify cooperating driver events activating PI3K/AKT/mTOR signaling | PNAS
Mutant p53 achieved Gain-of-Function by promoting tumor growth and immune escape through PHLPP2/AKT/PD-L1 pathway
Gastrointestinal Disorders | Free Full-Text | Prognostic Impact of TP53 Mutations and Tumor Mutational Load in Colorectal Cancer
LRP1B or TP53 mutations are associated with higher tumor mutational burden and worse survival in hepatocellular carcinoma
Diverse rescue potencies of p53 mutations to ATO are predetermined by intrinsic mutational properties | Science Translational Medicine
The p53 network: cellular and systemic DNA damage responses in cancer and aging: Trends in Genetics